This weekend, major disruptions are impacting Berlin's S-Bahn network due to ongoing construction and maintenance work.Service between Pankow and Karow will be suspended from Friday night until Monday early morning, with replacement buses operating on affected routes.Additional closures include sections between Treptower Park and Schöneweide and between Grünau and Schöneweide or Pankow and Hohen-Neuendorf, with the entire system expected to be affected until early Monday.