Brandon Aiyuk has been placed on the San Francisco 49ers' reserve/left squad list, a move that removes him from the active roster and effectively ends his time with the team for the foreseeable future.The reclassification follows the right knee ligament and meniscus tears he suffered in a hit last year, the 49ers' earlier decision to void $27 million in 2026 guarantees and growing statements from teammates such as George Kittle and Brock Purdy and staff including Kyle Shanahan and John Lynch that Aiyuk likely won't return this season.